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M.Sc. Robin Dinter

M.Sc. Robin Dinter Photo of M.Sc. Robin Dinter

Telephone
(+49)231 755-8067

Fax
(+49)231 755-8084

Address

Fakultät Bio- und Chemieingenieurwesen
Arbeitsgruppe ApparateDesign
Geschossbau 3

Room 512

Information

Curriculum Vitae

Robin Dinter has studied Chemical Engineering at the TU Dortmund University since 2013. He completed his bachelor thesis with the topic ‘Arduino based sensors and actuators for mass transfer studies in capillaries‘ at the Laboratory of Equipment Design. After a semester abroad at the Slovak University of Technology in Bratislava, Robin graduated with the master thesis ‘Application and Validation of an Automated Dosage System (ADoS) for Screening of DNA-tagged Substrates’ at the Laboratory of Equipment Design in 2019. Since 2020 he works as a research associate at the Laboratory of Equipment Design.

Research

  • In cooperation with Dr. Brunschweiger's group at the Department of Chemical Biology (CCB), an integrated and automated dosing system (ADoS) for DNA-encoded libraries (DELs) was developed as a completely open-source and off-the-shelf system based on a 3D‑printer model with microfluidic synthesis devices. The transfer of traditional laboratory batch workflow to continuous flow systems is significant, which provides enormous potential for advancing drug discovery using screening libraries. Toward laboratory automation and a fully integrated system, it is necessary to automate not only the DNA library synthesis or DNA-tagged reaction, but also pre- and post-synthesis steps such as purification or separation.
  • Besides, he develops a microfluidic toolbox including sensors, actuators, and remote-controlled setups for microfluidic experiments. The focus is on open-source equipment and do-it-yourself (DIY) lab-ware using microcontroller boards (Arduino).

Vacancies for Thesis

If you are interested in my field of research, please look at our moodle page for open vacancies.


Publications

Journal Articles

journalK. Götte, R. Dinter, L. Justen, N. Kockmann, A. Brunschweiger

Development of an Automatable Affinity Purification Process for DNA-Encoded Chemistry

ACS Omega, 2022, vol. -, p. -, https://doi.org/10.1021/acsomega.2c02906

journalW. Krieger, E. Bayraktar, O. Mierka, L. Kaiser, R. Dinter, J. Hennekes, S. Turek, N. Kockmann

Arduino‐based slider setup for gas–liquid mass transfer investigations: Experiments and CFD simulations

AIChE Journal, 2020, vol. 66, p. e16953, https://doi.org/10.1002/aic.16953

journalJ. Bobers, M. Klika Škopić, R. Dinter, P. Sakthithasan, L. Neukirch, C. Gramse, R. Weberskirch, A. Brunschweiger, N. Kockmann

Design of an Automated Reagent-Dispensing System for Reaction Screening and Validation with DNA-Tagged Substrates

ACS Combinatorial Science, 2020, vol. 22, p. 101-108, 10.1021/acscombsci.9b00207


Conference Proceedings

proceedingR. Dinter, S. Willems, M. Hachem, M. Mittelstädt, A. Brunschweiger, N. Kockmann

Two-Phase Flow Reaction System for Amide Coupling Towards Automated DNA-Encoded Chemistry

Chem. Ing. Tech., 2022, vol. 94, p. 1213-1234, 10.1002/cite.202255228

proceedingR. Dinter, L. Helwes, M. Pillath, N. Kockmann

Reaction Kinetic Investigation with Open-Source Microfluidic Conductivity Sensor

μFIP 2022, 2022, vol. 22CBMS-0001, p. 23, 978-1-7334190-3-1

proceedingW. Krieger, R. Dinter, G. Wiese, S. zur Horst-Meyer, N. Kockmann

Active Sensors for Gas-Liquid Mass Transfer Studies in Capillaries

ASME-ICNMM2018, 2018, p. V001T12A003, 10.1115/ICNMM2018-7659


Talks

talkR. Dinter, S. Willems, T. Nissalk, O. Hastuerk, A. Brunschweiger, N. Kockmann

Photoreactor Concept Developed by Rapid Prototyping for Microfluidic Flow Photochemistry

11th Workshop of Chemical and Biological Micro Laboratory Technology, 8.-10.03.2022, Ilmenau, Germany

talkN. Kockmann, R. Dinter, J. Bobers, K. Götte, S. Willems, A. Brunschweiger

Design and Application of an Integrated and Automated Dosing System (ADoS) for DNA-Encoded Libraries (DELs)

SPhERe, 4th Braunschweig International Symposium on Pharmaceutical Engineering Research, 15. - 17092021, Braunschweig (virtuel), Germany

talkJ. Bobers, M.K. Škopić, R. Dinter, P. Sakthithasan, L. Neukirch, C. Gramse, R. Weberskirch, A. Brunschweiger, N. Kockmann

Design of an Automated Reagent-Dispensing System for Reaction Screening and Validation with DNA-Tagged Substrates

EMBL Microfluidics Conference, 14.07.2020, virtual


Posters

posterR. Dinter, S. Willems, M. Hachem, M. Mittelstädt, A. Brunschweiger, N. Kockmann

Two-Phase Flow Reaction System for Amide Coupling Towards Automated DNA-Encoded Chemistry

(Bio)Process Engineering, 12.-15092022, Aachen, Germany

posterR. Dinter, L. Helwes, M. Pillath, N. Kockmann

Reaction Kinetic Investigation with Open-Source Microfluidic Conductivity Sensor

2. micro Flow and Interfacial Phenomena (µFIP) Conference, 20.-23062022, Irvine, California, USA

posterR. Dinter, S. Willems, T. Nissalk, O. Hastuerk, A. Brunschweiger, N. Kockmann

Photoreactor Concept Developed by Rapid Prototyping for Flow Photochemistry

ECCE 13 - 13th European Congress of Chemical Engineering, 20 - 23092021, virtual event


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Scientific Theses

MasterMahdi Hachem (Supervisor: Robin Dinter)

Development of a Continuous Two-Phase Flow Reaction System for Amide Coupling towards DNA-Encoded Chemistry

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 15.07.2022

MasterLennart Helwes (Supervisor: Robin Dinter)

Development of a microfluidic open-source conductivity sensor and investigation of the scope of application

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 10.12.2021

MasterLeon Justen (Supervisor: Robin Dinter)

Transfer of discontinuous purification steps in the field of DNA-encoded chemistry into an integrated and automated system using microwell plates and microchannels

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 03.12.2021

MasterThilo Nissalk (Supervisor: Robin Dinter)

Development of continuous and discontinuous photoreactors applied to photochemical radical and redox reactions

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 16.11.2021

BachelorThomas Schmidt (Supervisor: Robin Dinter)

Development of an automated remote-controlled acid-base titration using open-source equipment

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 29.01.2021

Show more scientific theses..