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M.Sc. Aljoscha Frede

M.Sc. Aljoscha Frede Photo of M.Sc. Aljoscha Frede

(+49)231 755-8067

(+49)231 755-8084


Fakultät Bio- und Chemieingenieurwesen
Arbeitsgruppe ApparateDesign
Geschossbau 3

Room 512


Curriculum Vitae

Aljoscha Frede has studied Biochemical Engineering at the TU Dortmund University since 2013. He completed his bachelor thesis with the topic ‘Investment Cost Estimation of Heat Exchanger Types During Phases of Early Engineering’ at the Laboratory of Plant and Process Design. After a research internship at Sanyo Chemical Industries, Kyoto, Aljoscha graduated with the master thesis ‘Development of a Methodology for the Investigation of Industrial Liquid-Liquid Systems in a Stirred-Pulsed Extraction column’ at the Laboratory of Equipment Design. Since 2019 he works as a research associate at the Laboratory of Equipment Design.


Micro reactors provide a high specific surface and low volume to enhance transport processes and enable safe handling of highly exothermic reactions. A drawback is that conventional sensor systems are rarely applicable in microchannels, which is why innovative and non-invasive solutions are desireable. The continuous, microfluidic calorimeter based on Seebeck elements allows the local and temporal resolution of heat flux profiles. Different operating modes of the reaction calorimeter provide thermodynamic and kinetic parameters of chemical reactions, which help to characterize reactors and aid reactor development.Explosionsansicht und Decisionmodule

Figure: Left: Exploded view of the microfluidic reaction calorimeter; right: Procedure for automated design of experiments and execution.

Open Thesis and Positions

If you are interested in my field of research, please look at our moodle page for open vacancies.


Journal Articles

journalT.A. Frede, M.C. Maier, N. Kockmann, H. Gruber-Wölfler

Advances in Continuous Flow Calorimetry

Org. Process Res. Dev., 2022, https://doi.org/10.1021/acs.oprd.1c00437

journalT.A. Frede, M. Dietz, N. Kockmann

Software-guided microscale flow calorimeter for efficient acquisition of thermokinetic data

J. Flow Chem., 2021, vol. 11, p. 321-332, https://doi.org/10.1007/s41981-021-00145-6

journalT.A. Frede, I. Burke, N. Kockmann

Software‐guided Microfluidic Reaction Calorimeter Based on Thermoelectric Modules

Chem. Ing. Tech., 2021, vol. 93, p. 1-5, https://doi.org/10.1002/cite.202000223


talkT.A. Frede, T. Brockhoff, M. Greive, N. Kockmann

Determination of Reaction Kinetics with an Automated Flow Calorimetry System

(Bio)Process Engineering, 12.-15.092022, Aachen, Germany

talkT.A. Frede, S. Höving, K. Boettcher, I. Aubel, N. Kockmann

Microcontroller-based Titration for Remote Lab

IEEE GeCon 2022, 11.-12.082022, Berlin/virtual, Germany

talkT.A. Frede, N. Kockmann

Automatisierte Durchflusskalorimetrie in kommerziell erhältlichen Mikroreaktoren mit thermoelektrischen Elementen

Sitzung des ProcessNet Arbeitsausschusses „Reaktionstechnik sicherheitstechnisch schwieriger Prozesse“, 13.04.2022, virtual


posterT.A. Frede, N. Link, N. Kockmann

Automated Flow Calorimeter based on Modular Microreactor Integration

ProcessNet Jahrestreffen Prozess-, Apparate- und Anlagentechnik 2021, 22.-23.112021, virtual, Germany

posterT.A. Frede, H. Köster, I. Burke, N. Kockmann

Automated Isothermal Reaction Calorimetry in Continuous Flow

ProcessNet Jahrestreffen Reaktionstechnik, 10.-12.05.2021, virtual, Germany

posterT.A. Frede, D. Sürig, N. Kockmann

Temperature Control of Microreactors in a Reaction Calorimeter Using Thermoelectric Modules

10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen, 21.-24.09.2020, virtual, Germany

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Scientific Theses

BachelorTobias Brockhoff (Supervisor: T.A. Frede)

Experimental Studies for the Parameter Determination of Exothermic Reactions using Flow Calorimetry

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 28.07.2022

BachelorRafael Reuß (Supervisor: T.A. Frede)

Charakterisierung eines mikrofluidischen Reaktionskalorimeters basierend auf FlowPlate® Lab und thermoelektrischen Elementen

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 26.01.2022

MasterN. Link (Supervisor: T.A. Frede)

Development of a Methodology for the Determination of Thermokinetic Data using Continuous Flow Reaction Calorimetry

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 21.10.2021

MasterH. Köster (Supervisor: T.A. Frede)

Automatisierte kalorimetrische Messungen von exothermen Reaktionen in kommerziell verfügbaren Mikroreaktoren

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 10.06.2021

MasterA. Alagu (Supervisor: T.A. Frede)

Thermal Characterization of the Microcalorimeter Base Plate

TU Dortmund, Fakultät BCI, Arbeitsgruppe Apparatedesign, 16.06.2021

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